SCIENTIFIC PUBLICATIONS

PRODUZIONE SCIENTIFICA 2019

Contribution of Infrapatellar Fat Pad and Synovial Membrane to Knee Osteoarthritis Pain

Authors:

Belluzzi, Elisa; Stocco, Elena; Pozzuoli, Assunta; Granzotto, Marnie; Porzionato, Andrea; Vettor, Roberto; De Caro, Raffaele; Ruggieri, Pietro; Ramonda, Roberta; Rossato, Marco; Favero, Marta; Macchi, Veronica

Source Title:

BIOMED RESEARCH INTERNATIONAL

DOI:

10.1155/2019/6390182

Development of Oxidized Polyvinyl Alcohol-Based Nerve Conduits Coupled with the Ciliary Neurotrophic Factor

Authors:

Porzionato, Andrea; Barbon, Silvia; Stocco, Elena; Dalzoppo, Daniele; Contran, Martina; De Rose, Enrico; Parnigotto, Pier Paolo; Macchi, Veronica; Grandi, Claudio; De Caro, Raffaele

Source Title:

MATERIALS

DOI: 

10.3390/ma12121996

Platelet-Rich Fibrin Scaffolds for Cartilage and Tendon Regenerative Medicine: From Bench to Bedside

Authors:

Barbon, Silvia; Stocco, Elena; Macchi, Veronica; Contran, Martina; Grandi, Francesca; Borean, Alessio; Parnigotto, Pier Paolo; Porzionato, Andrea; De Caro, Raffaele

Source Title:

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

DOI: 

10.3390/ijms20071701

PRODUZIONE SCIENTIFICA 2018

MHC MATCHING FAILS TO PREVENT LONG-TERM REJECTION OF IPSC-DERIVED NEURONS IN NONHUMAN PRIMATE

Authors:

Badin, Romina Aron; Bugi, Aurore; Williams, Susannah; Vadori, Marta; Michael, Marie; Jan, Caroline; Nassi, Alberto; Lecourtois, Sophie; Cozzi, Emanuele; Hantraye, Philippe; Perrier, Anselme L.

Source Title:

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

DOI: 

10.1136/jnnp-2018-EHDN.260

Cellular xenotransplantation of animal cells into people: benefits and risk

Authors:

Scobie, L.; Galli, C.; Gianello, P.; Cozzi, E.; Schuurman, H. -J.

Source Title:

REVUE SCIENTIFIQUE ET TECHNIQUE-OFFICE INTERNATIONAL DES EPIZOOTIES

DOI: 

10.20506/rst.37.1.2744

PRODUZIONE SCIENTIFICA 2017

Neu5Gc and alpha 1-3 GAL Xenoantigen Knockout Does Not Affect Glycemia Homeostasis and Insulin Secretion in Pigs

Authors:

Salama, Apolline; Mosser, Mathilde; Leveque, Xavier; Perota, Andrea; Judor, Jean-Paul; Danna, Corentin; Pogu, Sylvie; Moure, Anne; Jegou, Dominique; Gaide, Nicolas; Abadie, Jerome; Gauthier, Olivier; Concordet, Jean-Paul; Le Bas-Bernardet, Stephanie; Riochet, David; Le Berre, Ludmilla; Hervouet, Jeremy; Minault, David; Weiss, Pierre; Guicheux, Jerome; Brouard, Sophie; Bosch, Steffi; Lagutina, Irina; Duchi, Roberto; Lazzari, Giovanna; Cozzi, Emanuele; Blancho, Gilles; Conchon, Sophie; Galli, Cesare; Soulillou, Jean-Paul; Bach, Jean-Marie

Source Title:

DIABETES

DOI: 

10.2337/db16-1060

The mechanisms of rejection in solid organ transplantation

Authors:

Cozzi, Emanuele; Colpo, Anna; De Silvestro, Giustina

Source Title:

TRANSFUSION AND APHERESIS SCIENCE

DOI: 

10.1016/j.transci.2017.07.005

Posttransplant Lymphoproliferative Disorders in Neuronal Xenotransplanted Macaques

Authors:

Cavicchioli, L.; Ferraresso, S.; Westmoreland, S.; Kaliyaperumal, S.; Knight, H.; Crossan, C.; Scobie, L.; Danesi, A.; Vadori, M.; Trez, D.; Badin, R. Aron; Hantraye, P.; Cozzi, E.

Source Title:

VETERINARY PATHOLOGY

DOI: 

10.1177/0300985816669407

AAV9-mediated engineering of autotransplanted kidney of non-human primates

Authors:

Tomasoni, S.; Trionfini, P.; Azzollini, N.; Zentilin, L.; Giacca, M.; Aiello, S.; Longaretti, L.; Cozzi, E.; Baldan, N.; Remuzzi, G.; Benigni, A.

Source Title:

GENE THERAPY

DOI: 

10.1038/gt.2017.21

Translink: A Eu project aimed at studying the immune response in patient recipients of biological heart valves

Authors:

Cozzi, Emanuele; Roussel, Jean-Christian; Galinanes, Manuel; Costa, Cristina; Takeuchi, Yasu; Padler-Karavani, Vered; Breimer, Michael E.; Galli, Cesare; Pascual, Marta; Gerosa, Gino; Le Tourneau, Thierry; Bottio, Tomaso; Nonell-Canals, Alfons; Chen, Xi; Ritzwan, Manji; Nassi, Alberto; Vadori, Marta; Manez, Rafael; Soulillou, Jean-Paul

Source Title:

XENOTRANSPLANTATION

DOI: 

Involvement of Interleukin-17 During Acute and Chronic Allograft Rejection in Two Orthotopic Lung Transplantation Models

Authors:

Calabrese, F.; Lunardi, F.; Vuljan, S. E.; Vadori, M.; Zampieri, D.; Nannini, N.; Cozzi, E.; Rea, F.

Source Title:

JOURNAL OF HEART AND LUNG TRANSPLANTATION

DOI: 

PRODUZIONE SCIENTIFICA 2016

Progress in Clinical Encapsulated Islet Xenotransplantation

Authors:

Cooper, David K. C.; Matsumoto, Shinichi; Abalovich, Adrian; Itoh, Takeshi; Mourad, Nizar I.; Gianello, Pierre R.; Wolf, Eckhard; Cozzi, Emanuele

Source Title:

TRANSPLANTATION

DOI: 

10.1097/TP.0000000000001371

First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetesExecutive summary

Authors:

Hering, Bernhard J.; Cozzi, Emanuele; Spizzo, Thomas; Cowan, Peter J.; Rayat, Gina R.; Cooper, David K. C.; Denner, Joachim

Source Title:

XENOTRANSPLANTATION

DOI: 

10.1111/xen.12231

First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes - Chapter 1: update on national regulatory frameworks pertinent to clinical islet xenotransplantation

Authors:

Cozzi, Emanuele; Toenjes, Ralf R.; Gianello, Pierre; Buehler, Leo H.; Rayat, Gina R.; Matsumoto, Shinichi; Park, Chung-Gyu; Kwon, Ivo; Wang, Wei; O'Connell, Philip; Jessamine, Stewart; Elliott, Robert B.; Kobayashi, Takaaki; Hering, Bernhard J.

Source Title:

XENOTRANSPLANTATION

DOI: 

10.1111/xen.12222

Cell Therapy for Parkinson's Disease: A Translational Approach to Assess the Role of Local and Systemic Immunosuppression

Authors:

Badin, R. Aron; Vadori, M.; Vanhove, B.; Nerriere-Daguin, V.; Naveilhan, P.; Neveu, I.; Jan, C.; Leveque, X.; Venturi, E.; Mermillod, P.; Van Camp, N.; Dolle, F.; Guillermier, M.; Denaro, L.; Manara, R.; Citton, V.; Simioni, P.; Zampieri, P.; D'avella, D.; Rubello, D.; Fante, F.; Boldrin, M.; De Benedictis, G. M.; Cavicchioli, L.; Sgarabotto, D.; Plebani, M.; Stefani, A. L.; Brachet, P.; Blancho, G.; Soulillou, J. P.; Hantraye, P.; Cozzi, E.

Source Title:

AMERICAN JOURNAL OF TRANSPLANTATION

DOI: 

10.1111/ajt.13704

Indications and prospects of neural transplantation for chronic neurological diseases

Authors:

Vadori, Marta; Denaro, Luca; D'Avella, Domenico; Cozzi, Emanuele

Source Title:

CURRENT OPINION IN ORGAN TRANSPLANTATION

DOI: 

10.1097/MOT.0000000000000344

Effects of opioids on proximal renal tubular cells undergoing ATP depletion

Authors:

Bellini, Luca; Vadori, Marta; De Benedictis, Giulia Maria; Busetto, Roberto

Source Title:

JOURNAL OF PHARMACOLOGICAL SCIENCES

DOI: 

10.1016/j.jphs.2016.08.002

PRODUZIONE SCIENTIFICA 2015

The immunological barriers to xenotransplantation

Authors:

Vadori, M.; Cozzi, E.

Source Title:

TISSUE ANTIGENS

DOI: 

10.1111/tan.12669

Translational research for Parkinson's disease: The value of pre-clinical primate models

Authors:

Badin, Romina Aron; Vadori, Marta; Cozzi, Emanuele; Hantraye, Philippe

Source Title:

EUROPEAN JOURNAL OF PHARMACOLOGY

DOI: 

10.1016/j.ejphar.2015.03.038

Current status of neuronal cell xenotransplantation

Authors:

Vadori, Marta; Badin, Romina Aron; Hantraye, Philippe; Cozzi, Emanuele

Source Title:

INTERNATIONAL JOURNAL OF SURGERY

DOI: 

10.1016/j.ijsu.2015.09.052

ROLE OF NATURAL ANTI-AGAL ANTIBODY REPERTOIRE AND ANTIBODY-MEDIATED DAMAGE RISK IN THE CLINICAL USE OF ANIMAL-DERIVED TISSUES.

Authors:

Vadori, Marta; Nassi, Alberto; Ruffoni, Elena; Rigon, Francesca; Cozzi, Emanuele

Source Title:

TRANSPLANTATION

DOI:

Role of natural anti-alpha GAL antibody repertoire and antibody-mediated damage risk in the clinical use of animal-derived tissues

Authors:

Vadori, Marta; Nassi, Alberto; Ruffoni, Elena; Rigon, Francesca; Cozzi, Emanuele

Source Title:

XENOTRANSPLANTATION

DOI:

PRODUZIONE SCIENTIFICA 2014

Immunological Challenges and Therapies in Xenotransplantation

Authors:

Vadori, Marta; Cozzi, Emanuele

Source Title:

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE

DOI:

10.1101/cshperspect.a015578

Testing an unusual in vivo vessel network model: a method to study angiogenesis in the colonial tunicate Botryllus schlosseri

Authors:

Gasparini, Fabio; Caicci, Federico; Rigon, Francesca; Zaniolo, Giovanna; Manni, Lucia

Source Title:

SCIENTIFIC REPORTS

DOI:

10.1038/srep06460

Desensitization With Plasmapheresis and Anti-Cd20 for ABO Incompatible Kidney Transplantation From Living Donor: Experience of a Single Center in Italy

Authors:

Silvestre, C.; Furian, L.; Marson, P.; Tison, T.; Valente, M.; Marchini, F.; Rossi, B.; Bonfante, L.; Valerio, F.; Cozzi, E.; Rigotti, P.

Source Title:

TRANSPLANTATION PROCEEDINGS

DOI:

10.1016/j.transproceed.2014.07.063

PRODUZIONE SCIENTIFICA 2013

Human Amniotic Fluid Stem Cells Protect Rat Lungs Exposed to Moderate Hyperoxia

Authors:

Grisafi, Davide; Pozzobon, Michela; Dedja, Arben; Vanzo, Valentina; Tomanin, Rosella; Porzionato, Andrea; Macchi, Veronica; Salmaso, Roberto; Scarpa, Maurizio; Cozzi, Emanuele; Fassina, Ambrogio; Navaglia, Filippo; Maran, Claudio; Onisto, Maurizio; Caenazzo, Luciana; De Coppi, Paolo; De Caro, Raffaele; Chiandetti, Lino; Zaramella, Patrizia

Source Title:

PEDIATRIC PULMONOLOGY

DOI:

10.1002/ppul.22791

HO-1 Induction Improves The Type-1 Cardiorenal Syndrome in Mice With Impaired Angiotensin II-Induced Lymphocyte Activation

Authors:

Monu, Sumit R.; Pesce, Paola; Sodhi, Komal; Boldrin, Massimo; Puri, Nitin; Fedorova, Larisa; Sacerdoti, David; Peterson, Stephen J.; Abraham, Nader G.; Kappas, Attallah

Source Title:

HYPERTENSION

DOI:

10.1161/HYPERTENSIONAHA.111.00495

Features and full reversibility of the renal toxicity of the ruthenium-based drug NAMI-A in mice

Authors:

Vadori, Marta; Pacor, Sabrina; Vita, Francesca; Zorzet, Sonia; Cocchietto, Moreno; Sava, Gianni

Source Title:

JOURNAL OF INORGANIC BIOCHEMISTRY

DOI:

10.1016/j.jinorgbio.2012.09.018

Thromboelastographic evaluation of coagulative profiles in pig-to-monkey kidney xenotransplantation

Authors:

Spiezia, Luca; Boldrin, Massimo; Radu, Claudia; Bulato, Cristiana; Bertini, Diana; Bon, Maria; Campello, Elena; Vadori, Marta; Galli, Cesare; Gavasso, Sabrina; Nottle, Mark B.; Cowan, Peter J.; Cozzi, Emanuele; Simioni, Paolo

Source Title:

XENOTRANSPLANTATION

DOI:

10.1111/xen.12024

Clinicopathological findings in non-human primate recipients of porcine renal xenografts: quantitative and qualitative evaluation of proteinuria

Authors:

Pintore, Laura; Paltrinieri, Saverio; Vadori, Marta; Besenzon, Federica; Cavicchioli, Laura; De Benedictis, Giulia Maria; Calabrese, Fiorella; Cozzi, Emanuele; Nottle, Mark B.; Robson, Simon C.; Cowan, Peter J.; Castagnaro, Massimo

Source Title:

XENOTRANSPLANTATION

DOI:

10.1111/xen.12063

Generation of CMAH -/- piglets on GAL -/- genetic background

Authors:

Conchon, Sophie; Perota, Andrea; Concordet, Jean-Paul; Judor, Jean-Paul; Lagutina, Irina; Duchi, Roberto; Lazzari, Giovanna; Brouard, Sophie; Cozzi, Emanuele; Soulillou, Jean-Paul; Galli, Cesare

Source Title:

XENOTRANSPLANTATION

DOI:

Systemic immunosuppression plus local production of CTLA4-Ig to control rejection of transgenic pig neuroblasts in non-human primates

Authors:

Badin, Romina Aron; Vanhove, Bernard; Vadori, Marta; Fante, Fabio; Boldrin, Massimo; DeBenedictis, Giulia Maria; Cavicchioli, Laura; Sgarabotto, Dino; Jan, Caroline; Daguin, Veronique; Naveilhan, Philippe; Soulillou, Jean Paul; Denaro, Luca; Manara, Renzo; Zampieri, Paolo; D'Avella, Domenico; Plat, Martin; Venturi, Eric; Botte, Francoise; Rubello, Domenico; Hantraye, Philippe; Cozzi, Emanuele

Source Title:

XENOTRANSPLANTATION

DOI:

BORTEZOMIB ASSOCIATED WITH C5 INHIBITION WITH ECULIZUMAB ENABLES COMBINED CARDIAC-RENAL TRANSPLANTATION IN A HIGHLY IMMUNIZED CHILD

Authors:

Cozzi, Emanuele; Padalino, Massimo; Toscano, Giuseppe; Marson, Piero; Murer, Luisa; Pettenazzo, Andrea; Sgarabotto, Dino; Milanesi, Ornella; Angelini, Annalisa; Seveso, Michela; Gambino, Antonio; Tison, Tiziana; Ruffoni, Elena; Migoni, Angela; Feltrin, Giuseppe; Kirk, Richard; Piccolo, Giuseppe; De Silvestro, Giustina; Zanon, Giovanni F.; Giovanni, Stellin; Gerosa, Gino

Source Title:

TRANSPLANT INTERNATIONAL

DOI:

Coagulative profile in life supporting gal KO pig-to-primate kidney xenotransplantation

Authors:

Boldrin, Massimo; Gavasso, Sabrina; Vadori, Marta; Spiezia, Luca; Cavicchioli, Laura; Baldan, Nicola; De Benedictis, Giulia M.; Perota, Andrea; Stefani, Annalisa; Calabrese, Fiorella; Robson, Simon C.; Cowan, Peter; Galli, Cesare; Simioni, Paolo; Cozzi, Emanuele

Source Title:

XENOTRANSPLANTATION

DOI:

Lymphocryptovirus-associated post-transplant lymphoproliferative disorders and viral transcript expression in Cynomolgus macaque recipients of porcine neuronal precursors

Authors:

Cavicchioli, Laura; Westmoreland, Susan; Ferraresso, Serena; Kaliyaperumal, Sarav; Vadori, Marta; Crossan, Claire; Scobie, Linda; MariaDe Benedictis, Giulia; Stefani, Annalisa; Denaro, Luca; D'Avella, Domenico; Badin, Romina Aron; Cozzi, Emanuele

Source Title:

XENOTRANSPLANTATION

DOI:

Bone marrow and haemathological evaluation of 62 xenografted cynomolgus monkeys

Authors:

Gelain, Maria Elena; Salmaso, Arianna; Pintore, Laura; Fante, Fabio; Boldrin, Massimo; Vadori, Marta; Baldan, Nicola; Benedictis, Giulia MariaDe; Cozzi, Emanuele; Cavicchioli, Laura

Source Title:

XENOTRANSPLANTATION

DOI:

Ubiquitous CD39 expression is associated with reduced birth weight and viability of cloned transgenic piglets

Authors:

Lagutina, Irina; Perota, Andrea; Duchi, Roberto; Vadori, Marta; Cozzi, Emanuele; Calabrese, Fiorella; Lucchini, Franco; Lazzari, Giovanna; Galli, Cesare

Source Title:

XENOTRANSPLANTATION

DOI:

Long-term IgG response to porcine Neu5Gc-antigens in burn patients treated with porcine skin xenografts

Authors:

Scobie, Linda; Padler-Karavani, Vered; Bas-Bernardet, StephanieLe; Crossan, Claire; Blaha, Josef; Matouskova, Magda; Hector, Ralph; Cozzi, Emanuele; Vanhove, Bernard; Charreau, Beatrice; Blancho, Gilles; Bourdais, Ludovic; Tallacchini, Mariachiara; Ribes, Juan; Yu, Hai; Chen, Xi; Kracikova, Jitka; Broz, Ludmir; Hejnar, Jiri; Vesely, Pavel; Takeuchi, Yasuhiro; Varki, Ajit; Soulillou, Jean-Paul

Source Title:

XENOTRANSPLANTATION

DOI:

Life supporting pig-to-primate xenotransplantation model using transgenic GalT KO pigs: The Padua experience

Authors:

Vadori, Marta; Baldan, Nicola; Besenzon, Federica; Fante, Fabio; Boldrin, Massimo; Cavicchioli, Laura; MariaDe Benedictis, Giulia; Perota, Andrea; Stefani, Annalisa; Calabrese, Fiorella; Nottle, Mark B.; Robson, Simon C.; Cowan, Peter; Galli, Cesare; Cozzi, Emanuele

Source Title:

XENOTRANSPLANTATION

DOI:

PRODUZIONE SCIENTIFICA 2012

Refinement of a macaque transplantation model: application of a subcutaneous port as a means for long-term enteral drug administration and nutritional supplementation

Authors:

Fante, F.; Baldan, N.; De Benedictis, G. M.; Boldrin, M.; Furian, L.; Sgarabotto, D.; Ravarotto, L.; Besenzon, F.; Ramon, D.; Cozzi, E.

Source Title:

LABORATORY ANIMALS

DOI:

10.1258/la.2011.011007

PRODUZIONE SCIENTIFICA 2011

Xenotransplantation of Galactosyl-Transferase Knockout, CD55, CD59, CD39, and Fucosyl-Transferase Transgenic Pig Kidneys Into Baboons

Authors:

Le Bas-Bernardet, S.; Tillou, X.; Poirier, N.; Dilek, N.; Chatelais, M.; Devalliere, J.; Charreau, B.; Minault, D.; Hervouet, J.; Renaudin, K.; Crossan, C.; Scobie, L.; Cowan, P. J.; d'Apice, A. J. F.; Galli, C.; Cozzi, E.; Soulillou, J. P.; Vanhove, B.; Blancho, G.

Source Title:

TRANSPLANTATION PROCEEDINGS

DOI:

10.1016/j.transproceed.2011.09.024

Intracerebral xenotransplantation: recent findings and perspectives for local immunosuppression

Authors:

Leveque, Xavier; Cozzi, Emanuele; Naveilhan, Philippe; Neveu, Isabelle

Source Title:

CURRENT OPINION IN ORGAN TRANSPLANTATION

DOI:

10.1097/MOT.0b013e32834494b5

Effects of Long-Term Administration of Recombinant Human Protein C in Xenografted Primates

Authors:

Simioni, Paolo; Boldrin, Massimo; Gavasso, Sabrina; Seveso, Michela; Radu, Claudia; Bulato, Cristiana; Calabrese, Fiorella; Cavicchioli, Laura; Bertini, Diana; De Benedictis, Giulia M.; Besenzon, Federica; Baldan, Nicola; Spiezia, Luca; Plebani, Mario; Ancona, Ermanno; Cozzi, Emanuele

Source Title:

TRANSPLANTATION

DOI:

10.1097/TP.0b013e318200ba0e

Expression of a Musashi-Like Gene in Sexual and Asexual Development of the Colonial Chordate Botryllus schlosseri and Phylogenetic Analysis of the Protein Group

Authors:

Gasparini, Fabio; Shimeld, Sebastian M.; Ruffoni, Elena; Burighel, Paolo; Manni, Lucia

Source Title:

JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION

DOI:

10.1002/jez.b.21431

LONG TERM CLINICAL RECOVERY OF PARKINSON'S DISEASE FOLLOWING TRANSPLANTATION OF CTLA4-IG(+) PORCINE EMBRYONIC NEURONAL CELLS IN NON HUMAN PRIMATE

Authors:

Badin, Romina Aron; Padoan, Angelo; Vadori, Marta; Boldrin, Massimo; Cavicchioli, Laura; DeBenedictis, Giulia Maria; Fante, Fabio; Seveso, Michela; Sgarabotto, Dino; Jan, Caroline; Daguin, Veronique; Naveilhan, Philippe; Neveu, Isabelle; Soulillou, Jean-Paul; Giannello, Pierre; Vanhove, Bernard; Plat, Martine; Botte, Francoise; Venturi, Eric; Denaro, Luca; Manara, Renzo; Zampieri, Paolo; D'Avella, Domenico; Rubello, Domenico; Ancona, Ermanno; Hantraye, Philippe; Cozzi, Emanuele

Source Title:

TRANSPLANT INTERNATIONAL

DOI: